Outcomes of Education and Counseling for BRCA1 Testing

Women at increased risk for developing breast and/or ovarian cancer and their first degree relatives will be offered BRCA1 gene testing. This study proposes to evaluate psychological and behavioral aspects of their decision-making and the outcomes of the testing process. Knowledge and expectations will be assessed initially, followed by pre-test psychological assessment and an education and counseling session. Participants will be presented the choice of whether or not to undergo BRCA1 testing. Notification of test results will occur in person along with discussion of available surveillance options. Follow-up counseling evaluation and support will be provided. Psychological and behavioral outcomes will be reassessed at multiple timepoints following disclosure. Aspects of this research endeavor have been designed to complement an NCHGR/NCI extramural consortium and an NCHGR/NCI intramural collaboration both of which will address various aspects of risk notification and follow-up for hereditary breast, ovarian and colon cancer. Funded by NCHGR Intramural Program. Member of Cancer Genetic Studies Consortium--CGSC.