ELSI in Review • October 2023

About this listing

ELSI in Review is a listing of recently published reviews of the literature on key ELSI topics curated by CERA staff. Our October 2023 set explores communicating uncertain test results in cancer genetic counseling, defining and measuring genetic literacy, and more. If you would like your ELSI-relevant review featured in this communication, please contact us at [email protected]. You can find more reviews in the ELSIhub Publications database!

Prenatal Screening

• Johnston, M., Warton, C., Pertile, M. D., Taylor-Sands, M., Delatycki, M. B., Hui, L., Savulescu, J., & Mills, C. (2023). Ethical issues associated with prenatal screening using non-invasive prenatal testing for sex chromosome aneuploidy. Prenatal Diagnosis, 43(2), 226–234.
• Buckley, L. E., Hopkins, M. K., & Kuller, J. A. (2023). The evolving landscape of genetic carrier screening: Clinical considerations and challenges. Obstetrical & Gynecological Survey, 78(8), 483–489.
• Graf, W. D., Cohen, B. H., Kalsner, L., Pearl, P. L., Sarnat, H. B., Epstein, L. G., & the Ethics Committee of the Child Neurology Society. (2023). Fetal anomaly diagnosis and termination of pregnancy. Developmental Medicine & Child Neurology, 65(7), 900–907.
• Kessels, S. J. M., Carter, D., Ellery, B., Newton, S., & Merlin, T. L. (2020). Prenatal genetic testing for cystic fibrosis: A systematic review of clinical effectiveness and an ethics review. Genetics in Medicine, 22(2), 258–267.
• Bowman-Smart, H., Savulescu, J., Gyngell, C., Mand, C., & Delatycki, M. B. (2020). Sex selection and non-invasive prenatal testing: A review of current practices, evidence, and ethical issues. Prenatal Diagnosis, 40(4), 398–407.

Genetic Counseling

• Ballard, L. M., Band, R., & Lucassen, A. M. (2023). Interventions to support patients with sharing genetic test results with at-risk relatives: A synthesis without meta-analysis (SWiM). European Journal of Human Genetics, 31(9), Article 9.
• Culver, J. O., Bertsch, N. L., Kurz, R. N., Cheng, L., Pritzlaff, M., Rao, S. K., Stasi, S. M., Stave, C. D., & Sharaf, R. N. (2023). Systematic evidence review and meta-analysis of outcomes associated with cancer genetic counseling. Genetics in Medicine, Article 100980.
• Medendorp, N. M., van den Heuvel, L. M., Han, P. K. J., Hillen, M. A., & Smets, E. M. A. (2021). Communication skills training for healthcare professionals in providing genetic counseling: A scoping literature review. Patient Education and Counseling, 104(1), 20–32.
• Medendorp, N. M., van Maarschalkerweerd, P. E. A., Murugesu, L., Daams, J. G., Smets, E. M. A., & Hillen, M. A. (2020). The impact of communicating uncertain test results in cancer genetic counseling: A systematic mixed studies review. Patient Education and Counseling, 103(9), 1692–1708.

Genetic Literacy and Education

• Daly, B. M., & Kaphingst, K. A. (2023). Variability in conceptualizations and measurement of genetic literacy. PEC Innovation, 2, Article 100147.
• Medendorp, N. M., van den Heuvel, L. M., Han, P. K. J., Hillen, M. A., & Smets, E. M. A. (2021). Communication skills training for healthcare professionals in providing genetic counseling: A scoping literature review. Patient Education and Counseling, 104(1), 20–32.