00:30:15 David Lamb | ELSIhub: Welcome to ELSI Friday Forum! We are glad you will spend the hour with us. This series is held on the 2nd Friday of every month for one hour starting at 12 noon Eastern time. Immediately following the hour-long forum, the recording will stop and a more informal discussion will take place here in this same Zoom room, after the panel for 30 minutes.  We ask that all attendees please abide by the code of conduct, which can be found here: https://elsihub.org/news/code-conduct 00:30:58 David Lamb | ELSIhub: Visit ELSIhub to learn how to submit a AJOB target article proposal related to the topic of this seminar. https://elsihub.org/news/now-accepting-monthly-ajob-target-article-proposals-eff-topics 00:31:05 jack smith: Many thanks for this important information 00:31:20 David Lamb | ELSIhub: A compiled list of today’s resources published on ELSIhub:  https://elsihub.org/news/eff-resources-biogenome-science-international-scale-navigating-elsi-challenges Link to register for June’s EFF Session: https://us06web.zoom.us/meeting/register/JXFdHHhATX2sZfAq6d9YKQ Visit the ELSIhub website: https://elsihub.org/  Join our ELSI scholar directory: https://elsihub.org/form/submit-scholar  Subscribe to our newsletter: https://elsihub.org/news-and-events/newsletter 00:31:36 David Lamb | ELSIhub: ELSIhub Collections are essential reading lists on fundamental or emerging topics in ELSI, curated and explained by expert collection editors. Please use the link to access “Technologies to Operationalize Indigenous Data Sovereignty” curated by Māui Hudson, BHSc, AIT, MHSc, AUT (University of Waikato) and Stephanie Carroll, DrPH, MPH (University of Arizona). https://doi.org/10.25936/7sej-bj09 00:32:02 David Lamb | ELSIhub: If you wish to use Closed Captioning, please turn on (CC) at the bottom of your screen. Please note that links to most of the information referenced today, including speaker and moderator biographies will be put in the chat. You are also welcome to share your own resources on our topic there.  We encourage your questions, which you should submit using the Q&A button, which you will find at the bottom of your screen. In the Q&A box, you can register your enthusiasm for a question and elevate it up the list by using the UPVOTE button.   In the Chat, we will post links to resources referenced in today’s discussion and a resources list will be available on ELSIhub following the Forum. If you need assistance at any point, please email info@elsihub.org  at any time. 00:33:18 David Lamb | ELSIhub: MODERATOR: Martine Lappé, PhD   Link to biography: https://socialsciences.calpoly.edu/martine-lappe-2 Dr. Martine Lappé is an Associate Professor of Sociology and Science, Technology, and Society, in the Department of Social Sciences at the California Polytechnic State University, San Luis Obispo. She is also a Fellow in the Center on the Developing Child at Harvard University. Dr. Lappé is a feminist sociologist of science, health, and medicine and a previous postdoctoral fellow at Columbia’s Center for Excellence in ELSI Research. Her research focuses on the social and ethical dimensions of the contemporary life sciences, and their intersections with lived experiences of pregnancy and parenting.  From 2016-2022, Dr. Lappé was Principal Investigator of the K99/R00 grant titled “Behavioral Epigenetics in Children: Exploring the Social and Ethical Implications of Translation,” awarded by NHGRI’s Ethical, Legal, and Social Implications Program. 00:36:52 David Lamb | ELSIhub: PANELIST:Michael S. Kobor, PhD is a Professor in the Department of Medical Genetics at the University of British Columbia (UBC) and The Edwin S.H. Leong UBC Chair in Healthy Aging — a UBC President’s Excellence Chair. He has received many distinctions, including a Tier 1 Canada Research Chair in Social Epigenetics and an appointment as Fellow of the Canadian Institute for Advanced Research (CIFAR) Child and Brain Development Program. Until recently, Dr. Kobor served as the Sunny Hill BC Leadership Chair in Early Child Development, as well as the Director for Healthy Starts at BC Children's Hospital Research Institute. Dr. Kobor’s world-class, interdisciplinary research program employs a “society-to-cell” framework to better understand the mechanisms by which environmental exposures and life experiences can “get under the skin” to affect health and behaviour across the life course. 00:37:14 David Lamb | ELSIhub: PANELIST: Erika A. Waters, PhD, MPH Link to biography: https://publichealth.wustl.edu/people/erika-a-waters/ Dr. Erika Waters obtained a PhD in social psychology with a concentration in health from Rutgers University. As a part of my postdoctoral training at the National Cancer Institute, she obtained a Master of Public Health from Johns Hopkins School of Public Health. She began working at Washington University in St. Louis in 2009, and has been continually funded by the National Institutes of Health since 2011. Her research program seeks to understand how people think about health issues and how those thoughts influence their health-related decisions and behavior. Her scholarship informs health communication and behavior interventions that aim to improve health and reduce health disparities. 00:41:52 David Lamb | ELSIhub: Link to “Society to cell: How child poverty gets “Under the Skin” to influence child development and lifelong health”: https://www.sciencedirect.com/science/article/pii/S0273229721000381 00:43:28 David Lamb | ELSIhub: Link to “Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling”: https://pubmed.ncbi.nlm.nih.gov/19617551/ Link to “Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity”: https://pmc.ncbi.nlm.nih.gov/articles/PMC5903568/ Link to “Exposure to childhood abuse is associated with human sperm DNA methylation”: https://www.nature.com/articles/s41398-018-0252-1 00:43:36 David Lamb | ELSIhub: Link to “Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood”: https://pubmed.ncbi.nlm.nih.gov/28673994/ Link to “The Biological Embedding of Early-Life Socioeconomic Status and Family Adversity in Children’s Genome-Wide DNA Methylation”: https://www.tandfonline.com/doi/full/10.2217/epi-2018-0042 Link to “Epigenetics studies of fetal alcohol spectrum disorder: where are we now?”: https://pubmed.ncbi.nlm.nih.gov/28234026/ 00:44:41 David Lamb | ELSIhub: Link to “Epigenetic Vestiges of Early Developmental Adversity: Childhood Stress Exposure and DNA Methylation in Adolescence”: https://pmc.ncbi.nlm.nih.gov/articles/PMC3235257/ Link to “Epigenetic correlates of neonatal contact in humans”: https://pubmed.ncbi.nlm.nih.gov/29162165/ Link to “Cuddling babies, or not, affects infants' gene expression, B.C. study finds”: https://vancouversun.com/news/local-news/cuddling-babies-or-not-affects-infants-gene-expression-b-c-study-finds 00:47:52 David Lamb | ELSIhub: Link to “Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes”: https://pubmed.ncbi.nlm.nih.gov/30016711/#:~:text=aging%20of%20monocytes-,Early%2Dlife%20socioeconomic%20disadvantage%2C%20not%20current%2C%20predicts%20accelerated%20epigenetic,Psychoneuroendocrinology. Link to “Sex differences in epigenetic age in Mediterranean high longevity regions”: https://pubmed.ncbi.nlm.nih.gov/36506464/ Link to “Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging”: https://pubmed.ncbi.nlm.nih.gov/34425884/ Link to “Reversal of epigenetic aging and immunosenescent trends in humans”: https://pmc.ncbi.nlm.nih.gov/articles/PMC6826138/ Link to “Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial”: https://www.nature.com/articles/s43587-022-00357-y 00:49:08 David Lamb | ELSIhub: Link to “How Bryan Johnson, Who Wants to Live Forever, Sought Control via Confidentiality Agreements: https://www.nytimes.com/2025/03/21/technology/bryan-johnson-blueprint-confidentiality-agreements.html 00:49:50 David Lamb | ELSIhub: Link to “Open Mind, Open Genes: Exercising Your Epigenetic Power with Yoga”: https://www.whatisepigenetics.com/open-mind-open-genes-exercising-your-epigenetic-power-with-yoga/#google_vignette 00:51:46 David Lamb | ELSIhub: Please do not screenshot or otherwise record slides used in this presentation. 00:55:47 Esohe Irabor: Reacted to "Happy first EFF toda..." with 👍 01:02:54 David Lamb | ELSIhub: Link to “Will your Lifestyle Hurt your Grandchildren?”: ​​https://abcnews.go.com/Technology/lifestyle-hurt-grandchildren/story?id=25812009 Link to “Sperm passes dad's trauma and poor diet to his kids: Study reveals how a father's experience plays a key role in the way their child's cells develop”: https://www.dailymail.co.uk/health/article-6287201/Sperm-passes-dads-trauma-poor-diet-kids.html Link to “Poverty linked to epigenetic changes and mental illness”: https://www.nature.com/articles/nature.2016.19972 01:02:56 David Lamb | ELSIhub: Link to “Pregnant women who eat fast food every day are putting 'THREE generations at risk of obesity, heart disease and diabetes”: https://www.dailymail.co.uk/health/article-3653076/Pregnant-women-fast-food-everyday-putting-THREE-generations-risk-obesity-heart-disease-diabetes.html#:~:text=Pregnant%20women%20who%20eat%20fast,obesity%2C%20heart%20disease%20and%20diabetes' Link to “Pregnant 9/11 survivors transmitted trauma to their children”: https://www.theguardian.com/science/neurophilosophy/2011/sep/09/pregnant-911-survivors-transmitted-trauma#:~:text=Among%20the%20tens%20of%20thousands,mothers%20experienced%20on%20that%20day. 01:04:49 Dave Kaufman: 2 great talks, thank you! 01:06:00 Mousso SAVADOGO: great presentations, congratulations 01:06:25 Grace Morris: Hi all, We encourage you to put your questions in the Q&A box. If you can’t see it, click on the button with the ellipses in a circle over “More.” 01:06:41 Martine Lappe: Questions: What motivated you to study social epigenetics? And what have you taken away from studying the field so far - in terms of its ELSI impacts? 01:14:29 Yaomin Xu: How can we distinguish whether an epigenetic signal observed in a child is the result of early-life event versus being inherited from the parents? 01:14:33 Alham Saadat: Thank you for great grounding talks! You identified many categories of potential harms that can arise from this work what do you think are responsibilities of researchers to mitigate some of these harms? And related question, what role do you think community-engaged research can play as a part of this? 01:15:19 Grace Morris: Replying to "How can we distingui..." Hi Yaomin, to help the presenters see your question, please post it in the Q&A window. Thanks! 01:16:03 Subhashini Chandrasekharan: Reacted to "Thank you for great ..." with 👍 01:16:23 Yaomin Xu: Replying to "How can we distingui..." Done, thanks 01:16:54 Grace Morris: Reacted to "Done, thanks" with 👍 01:17:06 Grace Morris: Replying to "Thank you for great ..." Hi Alham, to help our speakers see your questions - please post it in the Q&A window. Thanks! 01:17:55 Alham Saadat: Reacted to "Hi Alham, to help ou..." with 👍🏽 01:19:38 Esohe Irabor: Thanks for joining us today for our session entitled: The ELSI of Social Epigenetics. I'm Esohe Irabor, PhD, the CERA Coordinator for today's webinar who opened and closed the session. Feel free to connect with me on LinkedIn: www.linkedin.com/in/esohe-irabor-phd-91180011b 01:21:07 Soo Shim: Esohe, Will there be a recording of this lecture available to view later? Thanks for coordinating an excellent lecture. 01:23:11 Esohe Irabor: Replying to "Esohe, Will there b..." There will be an abridged version of the recording (sans Dr. Water's presentation) of this lecture available for view later. 01:23:16 Esohe Irabor: Reacted to "Esohe, Will there b..." with 👍 01:23:33 Soo Shim: Epigenetic differences in stress response gene FKBP5 among children with abusive vs accidental injuries Todd M. Everson1,2, Kim Kaczor3, Kathi Makoroff4,5, Gabriel Meyers6, Norell Rosado7,8, Elizabeth Charleston7, Gina Bertocci9, Audrey Young7,10, Janet Flores11, Katie Lehnig11 and Mary Clyde Pierce7,8,11 01:23:36 Grace Morris: Replying to "Esohe, Will there b..." We will post the recording along with all the resources and links on the video page at elsihub.org. 01:23:48 Soo Shim: Pediatric Research; https://doi.org/10.1038/s41390-022-02441-w 01:28:42 David Lamb | ELSIhub: We will continue the discussion presently. At this time, we invite you to turn on your cameras and to raise your hands to ask questions and join the conversation. We look forward to seeing many of you. Visit ELSIhub to learn how to submit a AJOB target article proposal related to the topic of this seminar. https://elsihub.org/news/now-accepting-monthly-ajob-target-article-proposals-eff-topics 01:28:52 David Lamb | ELSIhub: Upcoming events that you can now register for: Our next ELSI Journal Club will be on May 30th at 12pm ET. Link to register: https://us06web.zoom.us/meeting/register/JeitdxXSRsyrjM5v3dxWyQ Link to register for June’s EFF Session, Rigor, Reproducibility and Responsibility: ELSI Questions in Population Data Practices:  https://us06web.zoom.us/meeting/register/JXFdHHhATX2sZfAq6d9YKQ 01:29:03 Graciela Cabana: Thank you! That was wonderful. 01:29:21 David Lamb | ELSIhub: Resources and links from today’s session: https://elsihub.org/news/eff-resources-elsi-social-epigenetics 01:29:25 Aantaki Raisa: very insightful talks, thank you! 01:29:30 Dave Kaufman: Reacted to "Thank you! That was ..." with 👍 01:29:54 David Lamb | ELSIhub: Link to submit an ELSI Shoutout:  https://docs.google.com/forms/d/e/1FAIpQLSdJculh5l2LIbDfXwefWWEdmurUnnuxOqMIy-4utRpNN68R6A/viewform Visit the ELSIhub website: https://elsihub.org/  Join our ELSI scholar directory: https://elsihub.org/form/submit-scholar  Subscribe to our newsletter: https://elsihub.org/news-and-events/newsletter     Follow us on Bluesky https://bsky.app/profile/elsihub.bsky.social and post your favorite moments using #ELSIFridayForum  Follow us on Twitter @ELSIhub: https://twitter.com/ELSIhub and tweet your favorite moments using #ELSIFridayForum  Follow us on LinkedIn: https://www.linkedin.com/company/elsihub/ We invite you to browse ELSIhub Collections. ELSIhub Collections are essential reading lists on fundamental or emerging topics in ELSI, curated and explained by expert Collection Editors, often paired with ELSI trainees: https://elsihub.org/resources/collections There you will also find the recording and transcript of this forum and related references.