This core developed by Jennifer B McCormick examines fundamental concepts in scholarship on the ethical, legal/policy, social implications of genetic and genomic science. These include how the field of genetics has evolved into the current era of translational genomics and personalized medicine, genetic discrimination and stigmatization, existing legal/regulatory frameworks, race and ethnicity, return of research results, return of incidental findings from genomic sequencing, individual’s right to know/right not to know, and data ownership and sharing.