ELSI in Review • December 2024

About this listing

ELSI in Review is a listing of recently published reviews of the literature on key ELSI topics curated by CERA staff. Our December 2024 set explores ethical aspects of human genome research in sports, payer perspectives on genomic testing, and more. If you would like your ELSI-relevant review featured in this communication, please contact us at [email protected]. You can find more reviews in the ELSIhub Publications database!

Genetic Testing and Screening

• Gallois, H., Ravitsky, V., Roy, M.-C., & Laberge, A.-M. (2024). Defining ethical criteria to guide the expanded use of Noninvasive Prenatal Screening (NIPS): Lessons about severity from preimplantation genetic testing. European Journal of Human Genetics. Advance online publication.
• Mai, C.-W., Sridhar, S. B., Karattuthodi, M. S., Ganesan, P. M., Shareef, J., Lee, E. L., & Armani, K. (2024). Scoping review of enablers and challenges of implementing pharmacogenomics testing in the primary care settings. BMJ Open, 14(11), Article e087064.
• Ioannou, K. I., Constantinidou, A., & Chatzittofis, A. (2024). Genetic testing in psychiatry, the perceptions of healthcare workers and patients: A mini review. Frontiers in Public Health, 12, Article 1466585.
• Rensink, M., Bolt, I., & Schermer, M. (2024). Predicting age of onset and progression of disease in late-onset genetic neurodegenerative diseases: An ethics review and research agenda. European Journal of Human Genetics, 32(11), 1361–1370.
• Wiedower, J., Smith, H. S., Farrell, C. L., Parker, V., Rebek, L., & Davis, S. C. (2024). Payer perspectives on genomic testing in the United States: A systematic literature review. Genetics in Medicine. Advance online publication.
• Wang, M., Jiang, S., Li, B., Parkinson, B., Lu, J., Tan, K., Gu, Y., & Li, S. (2024). Synthesized economic evidence on the cost-effectiveness of screening familial hypercholesterolemia. Global Health Research and Policy, 9(1), Article 38.

Precision Medicine

• Sibomana, O. (2024). Genetic diversity landscape in African population: A review of implications for personalized and precision medicine. Pharmacogenomics and Personalized Medicine, 17, 487–496.
• Adebesin, F., & Oluwadele, D. (2024). Ethical implications of precision medicine for Society 5.0: A systematic review. In K. Hinkelmann & H. Smuts (Eds.), Society 5.0 (pp. 1–13). Springer Nature Switzerland.

Genetic Cancer Care

• Smit, A. K., Gokoolparsadh, A., McWhirter, R., Newett, L., Milch, V., Hermes, A., McInerney-Leo, A., & Newson, A. J. (2024). Ethical, legal, and social issues related to genetics and genomics in cancer: A scoping review and narrative synthesis. Genetics in Medicine, 26(12), Article 101270.
• Park, S.-Y., Kim, Y., Katapodi, M. C., Kim, Y.-J., Chae, H., Choi, Y.-J., Ryu, K. H., Lee, E.-G., Kong, S.-Y., & Jung, S.-Y. (2024). Healthcare professionals’ learning needs and perspectives on essential information in genetic cancer care: A systematic review. Cancers, 16(11), Article 11.

Genomics Research

• Calluori, S., Heimke, K. K., Caga-anan, C., Kaufman, D., Mechanic, L. E., & McAllister, K. A. (2024). Ethical, legal, and social implications of gene-environment interaction research. Genetic Epidemiology. Advance online publication.
• Nasir, B. F., Vinayagam, R., Massi, L., Nagaraj, S. H., Toombs, M., & Rae, K. M. (2024). A systematic review exploring empirical pharmacogenomics research within global Indigenous populations. Molecular Genetics & Genomic Medicine, 12(10), Article e70018.
• Pra, R. D., O’Brien, P., Nguyen, H. X. T., Luke, J., Smith, R. A., Withall, A., Radford, K., Lavrencic, L. M., Watson, R., Flicker, L., & Logiudice, D. (2024). Culturally safe and ethical biomarker and genomic research with Indigenous peoples—A scoping review. BMC Global and Public Health, 2(1), 72.
• Bojarczuk, A. (2024). Ethical aspects of human genome research in sports—A narrative review. Genes, 15(9), Article 9.