ELSI in Review • February 2025

About this listing

ELSI in Review is a listing of recently published reviews of the literature on key ELSI topics curated by CERA staff. Our February 2025 set explores experiences of perinatal genetic screening for people from migrant and refugee backgrounds, genomic literacy gaps among cancer patients, and more. If you would like your ELSI-relevant review featured in this communication, please contact us at [email protected]. You can find more reviews in the ELSIhub Publications database!

Cancer Genetics

• Diez de los Rios de la Serna, C., Dowling, M., McNamara, N., Ivory, J. D., Hanhauser, Y., Murphy, M., & Dean, M. (2025). A scoping review of parents’ disclosure of BRCA1/2 genetic alteration test results to underage children. Patient Education and Counseling, 131, Article 108561.
• Nikitara, K., Cardoso, M. L., Vicente, A. M., Batalha Silva Rasga, C. M., De Angelis, R., Chamoun Morel, Z., De Nicolo, A., Nomikou, M., Karamanidou, C., & Kakalou, C. (2025). Exploring literacy and knowledge gaps and disparities in genetics and oncogenomics among cancer patients and the general population: A scoping review. Healthcare, 13(2), Article 2.
• Thomas, C. E., & Peters, U. (2024). Genomic landscape of cancer in racially and ethnically diverse populations. Nature Reviews Genetics. Advance online publication.
• Berkman, J., DeBortoli, E., Steinberg, J., Milch, V., Yanes, T., & McInerney-Leo, A. (2025). Mainstreaming cancer genomic testing: A scoping review of the acceptability, efficacy, and impact. Clinical Genetics, 107(2), 123–135.

Artificial Intelligence

• Corfmat, M., Martineau, J. T., & Régis, C. (2025). High-reward, high-risk technologies? An ethical and legal account of AI development in healthcare. BMC Medical Ethics, 26(1), Article 4.
• Sasseville, M., Ouellet, S., Rhéaume, C., Sahlia, M., Couture, V., Després, P., Paquette, J.-S., Darmon, D., Bergeron, F., & Gagnon, M.-P. (2025). Bias mitigation in primary health care artificial intelligence models: Scoping review. Journal of Medical Internet Research, 27(1), Article e60269.
• Wilhelm, C., Steckelberg, A., & Rebitschek, F. G. (2025). Benefits and harms associated with the use of AI-related algorithmic decision-making systems by healthcare professionals: A systematic review. The Lancet Regional Health – Europe, 48, Article 101145.

Genetic Screening and Genetic Counseling

• Kanga-Parabia, A., Archibald, A. D., Biggs, L. J., Lewis, S., Tutty, E., & Dawson-McClaren, B. (2025). Experiences of perinatal genetic screening for people from migrant and refugee backgrounds: A scoping review. European Journal of Human Genetics. Advance online publication.
• Cook, C. B., Pistawka, C., Elliott, A. M., Austin, J., Knoppers, B., Lynd, L. D., Dey, A., Adam, S., Bansback, N., Birch, P., Clarke, L., Dragojlovic, N., Friedman, J., Lambert, D., Pullman, D., Virani, A., Wasserman, W., Zawati, M., & Elliott, A. M. (2025). The impact of genetic counselor involvement in genetic and genomic test order review: A scoping review. Genetics in Medicine, 27(3), Article 101354.
• Ireland-Blake, N., Cram, F., Dew, K., Bacharach, S., Snelling, J., Stone, P., Buchanan, C., & Filoche, S. (2025). “Knowledge was clearly associated with education.” Epistemic positioning in the context of informed choice: A scoping review and secondary qualitative analysis. BMC Medical Ethics, 26, Article 1.

Policy

• Basnayake Ralalage, P., Mitchell, T., Zammit, C., Baynam, G., Kowal, E., Masey, L., McGaughran, J., Boughtwood, T., Jenkins, M., Pratt, G., & Ferdinand, A. (2024). “Equity” in genomic health policies: A review of policies in the international arena. Frontiers in Public Health, 12, Article 1464701.
• Greco, A., Frederix, G. W. J., Hooft, L., & Ten Ham, R. M. T. (2024). A systematic review of challenges and opportunities in the implementation of managed entry agreements for advanced therapy medicinal products. Clinical Therapeutics. Advance online publication.

Biobanking and Data Sharing

• Andanda, P., & Mlotshwa, L. (2024). Streamlining the ethical-legal governance of cross-border health data sharing during global health emergencies. Research Ethics, 20(4), 812–834.
• Borkhataria, C. H., Sharma, S., Vaja, P., Tank, C., Mori, D., Patel, K., & Kyada, A. (2025). Quality management, ethical considerations, and emerging challenges in genomics and biobanking: A comprehensive review. Clinica Chimica Acta, 569, Article 120161.
• Lay, W., Gasparini, L., Siero, W., & Hughes, E. K. (2025). A rapid review of the benefits and challenges of dynamic consent. Research Ethics, 21(1), 180–202.
• Obiora, O. L., Shead, D. A., & Olivier, B. (2024). Data sharing considerations and practice among health researchers in Africa: A scoping review. DIGITAL HEALTH, 10.
• Teodorowski, P., Jones, E., Tahir, N., Ahmed, S., Rodgers, S. E., & Frith, L. (2024). Public involvement and engagement in big data research: Scoping review. Journal of Participatory Medicine, 16(1), Article e56673.