ELSI in Review • March 2024

About this listing

ELSI in Review is a listing of recently published reviews of the literature on key ELSI topics curated by CERA staff. Our March 2024 set explores liability in applications of medical AI, communicating genetic risk information to patients, and more. If you would like your ELSI-relevant review featured in this communication, please contact us at [email protected]. You can find more reviews in the ELSIhub Publications database!

Genetic Testing

• Fahy, N., Rice, C., Lahiri, N., Desai, R., & Stott, J. (2023). Genetic risk for Huntington Disease and reproductive decision-making: A systematic review. Clinical Genetics, 104(2), 147–162.
• Aref, H. A. T., Makowsky, M. J., Kung, J. Y., & Guirguis, L. M. (2023). Mapping the implementation of pharmacogenomic testing in community pharmacies 2003-2021 using the Theoretical Domains Framework: A scoping review. Journal of the American Pharmacists Association, 63(2), 459-476.e6.
• Pichler, T., Mumm, F., Dehar, N., Dickman, E., Díez de Los Ríos de la Serna, C., Dinkel, A., Heinrich, K., Hennink, M., Parviainen, A. D., Raske, V., Wicki, N., & Moore, A. C. (2024). Understanding communication between patients and healthcare professionals regarding comprehensive biomarker testing in precision oncology: A scoping review. Cancer Medicine. Advance online publication.
• Cilli, E., Guerra, F., Ranieri, J., Brancati, F., & Di Giacomo, D. (2024). Patient perspective in perceived comparative genetic mutation risk: An exploratory review. Clinical Genetics. Advance online publication.
• IItis, A. S., Lewis, A., Neely, S., Seaton, S. W., & Jeong, S. H. (2023). Applying genetic and genomic tools to psychiatric disorders: A scoping review. HEC Forum, 35(3), 293–308.
• Miller, E. G., Young, J. L., Rao, A., Ward-Lev, E., & Halley, M. C. (2023). Demographic characteristics associated with perceptions of personal utility in genetic and genomic testing: A systematic review. JAMA Network Open, 6(5), Article e2310367.

Artificial Intelligence

• Cestonaro, C., Delicati, A., Marcante, B., Caenazzo, L., & Tozzo, P. (2023). Defining medical liability when artificial intelligence is applied on diagnostic algorithms: A systematic review. Frontiers in Medicine, 10, Article 1305756.
• Brereton, T. A., Malik, M. M., Lifson, M., Greenwood, J. D., Peterson, K. J., & Overgaard, S. M. (2023). The role of artificial intelligence model documentation in translational science: Scoping review. Interactive Journal of Medical Research, 12(1), Article e45903.
• Weidener, L., & Fischer, M. (2023). Teaching AI ethics in medical education: A scoping review of current literature and practices. Perspectives on Medical Education, 12(1), 399–410.

Direct-to-Consumer Genetic Testing

• Nagappan, A., Kalokairinou, L., & Wexler, A. (2024). Ethical issues in direct-to-consumer healthcare: A scoping review. PLOS Digital Health, 3(2), Article e0000452.
• Nolan, J. J., & Ormondroyd, E. (2023). Direct-to-consumer genetic tests providing health risk information: A systematic review of consequences for consumers and health services. Clinical Genetics, 104(1), 3–21.
• Hoxhaj, I., Stojanovic, J., & Boccia, S. (2023). European citizens’ perspectives on direct-to-consumer genetic testing: An updated systematic review. European Journal of Public Health, 33(5), 947–953.