ELSI in Review • March 2025

About this listing

ELSI in Review is a listing of recently published reviews of the literature on key ELSI topics curated by CERA staff. Our March 2025 set explores the ELSI of forensic genetic investigations, integrating ELSI study teams in pediatric genomic research, and more. If you would like your ELSI-relevant review featured in this communication, please contact us at [email protected]. You can find more reviews in the ELSIhub Publications database!

Research Ethics

• Hernandez, R. G., Guambaña, S., VonDran, M. W., Van Hoose, P. M., Bell, T. J., & Faith, M. A. (2025). Integrating ELSI study teams in paediatric genomic research efforts. Nature Reviews Genetics. Advance online publication.
• Yakubu, A., Adedeji, I., Maduka, O. C., Jegede, A., & Adebamowo, C. (2024). Ethical issues in genomics research in persons with Alzheimer’s Disease/Alzheimer’s Disease-related dementia (AD/ADRD): A systematic review. BMC Medical Ethics, 25(1), 138.

Global Perspectives

• Abozaid, G. M., Kerr, K., Alomary, H., Al-Omar, H. A., & McKnight, A. (2025). Global insight into rare disease and orphan drug definitions: A systematic literature review. BMJ Open, 15, Article e086527.
• Lopes-Cendes, I., & Oliveira, T. C. de. (2025). Inequalities and inclusion in genomics applied to healthcare: A Latin American perspective. Annual Review of Genomics and Human Genetics. Advance online publication. 

Artificial Intelligence

• Marko, J. G. O., Neagu, C. D., & Anand, P. B. (2025). Examining inclusivity: The use of AI and diverse populations in health and social care: A systematic review. BMC Medical Informatics and Decision Making, 25(1), Article 57.
• Weissman, G. E. (2025). Evaluation and regulation of artificial intelligence medical devices for clinical decision support. Annual Review of Biomedical Data Science. Advance online publication.

Public Engagement

• Godino, L., Turchetti, D., Gentili, V., Chiari, P., & Palese, A. (2025). Public perspectives on healthcare professional-directed communication of hereditary genetic risks: A mixed-method systematic review. European Journal of Human Genetics. Advance online publication.
• Iltis, A. S., Baker, L. L., Baldwin, K., Cruz, L., Yaeger, L. H., & DuBois, J. M. (2025). Approaches to engaging faith communities in public health efforts regarding vaccination, genetics, and colorectal cancer: A systematic review. BMC Public Health, 25, Article 703.

Forensic Genetics

• Fuente, C. M. de la, & Palomo-Díez, S. (2025). Do forensic genetic markers disclose more information about us than they should? (A review). International Journal of Legal Medicine. Advance online publication.
• Sessa, F., Chisari, M., Esposito, M., Karaboue, M. A. A., Salerno, M., & Cocimano, G. (2024). Ethical, legal and social implications (ELSI) regarding forensic genetic investigations (FGIs). Journal of Academic Ethics. Advance online publication.