Type
Journal Article
Title
The landscape of reported VUS in multi-gene panel and genomic testing: Time for a change
External Link
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Year:
Date
2023
Journal Book Publisher Name
Genetics in Medicine
Description
Description
Rehm and colleagues analyzed aggregate genetic testing results from 19 North American laboratories over a two-year period and found that exome and genome sequencing tests (ES/GS) yield a lower rate of reported variants of uncertain significance (VUS) compared to multi-gene panel (MGP) tests. They recommend changes to MGP reporting and provider education.