Gene Modification Therapy Scenarios for Parents of People with Down Syndrome

Michie and Allyse developed five scenarios that describe existing and hypothetical interventions for symptoms of Down syndrome (DS): 1) prenatal physical intervention, 2) prenatal cognitive intervention, 3) pediatric physical intervention, 4) pediatric cognitive intervention, and 5) Adult treatment to reduce Alzheimers risk. Participants, consisting of family members of people with DS, were asked to choose whether or not they would have the intervention and explain their reasoning behind their choice.