CSER Phase 1: Consent Form (Colorectal Cancer/Polyposis) - The NEXT (New EXome Technology in Medicine) Medicine Study

This consent form for the NEXT Medicine Study is designed for individuals with colorectal cancer/polyposis or a close family member with the syndrome. It contains information about the study and the researchers involved, the purpose of the study, what is involved in participating, potential risks and benefits of participating, financial questions and answers related to the study, and who to contact with questions.

CSER Phase 1: Consent Form: (Adult Subject) Relatives of a Study Subjects - NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis and Research

This consent form from the NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis study is designed for the adult relatives of NCGENES study participants with a genetic test result containing a variant of uncertain significance (VUS). This consent is for the relative to be tested for the VUS previously identified in the NCGENES study participant, not enrollment in the full NCGENES study.

CSER Phase 1: Assent Form: (Ages 15-17) Relatives of a Study Subjects - NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis and Research

This assent form from the NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis study is designed for the adolescent (aged 15-17) relatives of NCGENES study participants with a genetic test result containing a variant of uncertain significance (VUS). This assent is for the relative to be tested for the VUS previously identified in the NCGENES study participant, not enrollment in the full NCGENES study.

CSER Phase 1: Assent Form: (Ages 7-14) Relatives of a Study Subjects - NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis and Research

This assent form from the NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis study is designed for the 7 - 14 year old relatives of NCGENES study participants with a genetic test result containing a variant of uncertain significance (VUS). This assent is for the relative to be tested for the VUS previously identified in the NCGENES study participant, not enrollment in the full NCGENES study.

CSER Phase 1: Parental Consent for Child to Participate in a Research Study, Minor Subjects- Relatives of Study Subject - NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis and Research

This parental consent form from the NCGENES: A Next-Generation Sequencing Platform for Genetic Diagnosis study is designed for the minor relatives of NCGENES study participants that received a genetic test result containing a variant of uncertain significance (VUS). This parental consent is for the minor relative to be tested for the VUS previously identified in the NCGENES study participant, not enrollment in the full NCGENES study.

CSER Phase 1: Adult/parent consent with assent form - Personalized Medicine Based on Molecular Profiling of Patients with Cancer

This consent/ assent form for adults, adolescents, and parents of minors in the Personalized Medicine Based on Molecular Profiling of Patients with Cancer study includes consent to the use of tumor cells to create cell lines, consent to additional analysis of the sequencing data for research purposes, and "right not to know" provisions for results that may have significance for biological family members and results that may have potential medical impact.

CSER Phase 1: Consent form - Personalized Oncology Through High-throughput Sequencing: MI-ONCOSEQ (Michigan Oncology Sequencing Center)

This consent form for the Personalized Oncology Through High-throughput Sequencing: MI-ONCOSEQ (Michigan Oncology Sequencing Center) study includes authorization to create cell lines from participant tumor tissue and to store clinical information and samples for use in ongoing research.

CSER Phase 1: Informed Consent Document - Genomic Diagnosis in Children with Developmental Delay

This informed consent document for parents and minors in the Genomic Diagnosis in Children with Developmental Delay study includes standard consent language plus consent to storage of specimens for future use, to be contacted about new research studies, and to share genetic and health information in the dbGaP database.

CSER Phase 1: Female Research Consent and Authorization Form - NextGen: Clinical Implementation of Carrier Testing Using Genome Sequencing

This research consent and authorization form for enrollment in the NextGen trial by female Kaiser Permanente patients who requested carrier testing for inherited condition or disease before getting pregnant or during pregnancy.

CSER Phase 1: Male Research Consent and Authorization Form - NextGen: Clinical Implementation of Carrier Testing Using Genome Sequencing

This research consent and authorization form for enrollment in the NextGen trial by male partners of female Kaiser Permanente patients who requested carrier testing for inherited condition or disease before getting pregnant or during pregnancy.