Actionable Ethics Oversight for Human-Animal Chimera Research

NIH Sep 12, 2018 | R01

Actionable Ethics Oversight for Human-Animal Chimera Research

Principal Investigator(s): HYUN, INSOO , JOHNSTON, JOSEPHINE MARGUERITE (contact), MASCHKE, KAREN JOANN;

Institution: HASTINGS CENTER, INC.

FOA Number: PA-17-444

Abstract

PROJECT NARRATIVE Advances in genome editing, embryology, and stem cell science are making it possible to imagine, and create, new kinds of human-animal chimeras that are both more biologically and more ethically complex than previously created chimeras. This project aims to develop clear, reasoned, and practical recommendations and educational materials to assist researchers, research institutions and their oversight bodies, funders and the public in identifying, understanding, and managing the ethical issues associated with human-animal chimera research.

FUNDING AGENCY:

Funder:
NIH

Institute:
NATIONAL HUMAN GENOME RESEARCH INSTITUTE

Funding Type:
R01

Project Number:
R01HG010168

Start Date:
Sep 12, 2018

End Date:
Jun 30, 2021

PROJECT TERMS:

Adopted, animal breeding, Animal Experimentation, Animal Welfare, Animals, Area, base, Biological, Brain, Cells, Chimera organism, Complex, Conflict (Psychology), design, Development, education resources, Educational Materials, Embryo, Embryology, Ethical Issues, Ethics, experience, fetal, Genes, Genetic Engineering, genome editing, Germ Cells, Goals, Guidelines, Human, human stem cells, IACUC, Influentials, Institution, intergenerational, International, Interview, Knowledge, Laws, Learning Module, Literature, Measures, member, Methods, Morals, Neuraxis, Organ, Paper, Policies, Protocols documentation, Published Comment, Recommendation, Regulation, Research, Research Personnel, Research Project Grants, response, Risk, Science, Science of genetics, Scientific Advances and Accomplishments, Scientist, sex, Societies, Stem Cell Research, Stem cells, Structure, System, Techniques, Uncertainty, United States National Academy of Sciences, Vertebrates, working group

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Actionable Ethics Oversight for Human-Animal Chimera Research

Abstract

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PROJECT TERMS:

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