• NIH Aug 13, 2019 | R21

    Developing Clinical Translational Tools to Communicate Genetic Risk to Individuals who are at Clinical High Risk for Psychosis

    Principal Investigator(s): YANG, LAWRENCE H;

    Institution: NEW YORK UNIVERSITY

    FOA Number: PA-18-344

    Abstract

    While great strides are being made in identifying early signs that place people at a ?high risk state? for different illness conditions, at the same time, advances are being made in the identification of genes associated with ?high-risk states?. This study proposes to develop two innovative clinical tools that could greatly facilitate dissemination of a beneficial genetic malleability framing to high-risk youth in order to encourage increased treatment engagement and uptake of healthy behaviors. The impact of genetic information assumes special importance in the ?high-risk state? because achieving the best possible outcome is more likely if individuals actively choose to engage in beneficial treatment and health-promoting behaviors.

    FUNDING AGENCY:

    Funder:
    NIH

    Institute:
    NATIONAL HUMAN GENOME RESEARCH INSTITUTE

    Funding Type:
    R21

    Project Number:
    R21HG010420

    Start Date:
    Aug 13, 2019

    End Date:
    Jul 31, 2021

    PROJECT TERMS:

    Abbreviations, Address, Age, Attenuated, base, Behavior, Behavioral, behavioral outcome, Belief, brca gene, Breast Cancer gene, Breast Cancer Risk Factor, Clinical, computerized, Computers, Control Groups, design, Development, Diabetes Mellitus, Diagnosis, Disease, Distant, Early Intervention, Effectiveness, efficacy testing, essentialism, Exposure to, Future, Gene Expression, Genes, Genetic, Genetic Determinism, genetic discrimination, genetic information, Genetic Risk, Goals, Health, Health Promotion, high risk, improved, improved outcome, Individual, innovation, Link, Literature, malleable risk, Manuals, modifiable risk, National Human Genome Research Institute, non-genetic, Outcome, Participant, prevent, Preventive, primary outcome, protective behavior, psychogenetics, Psychotic Disorders, Public Health, Randomized Clinical Trials, Research, response, Risk, Risk Behaviors, Risk Factors, risk variant, Safety, Sampling, secondary outcome, Self Management, social stigma, Stress, Testing, Time, tool, Training, uptake, Work, young adult, Youth

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