Polygenic Risk Prediction in Diverse Populations and Contexts: Scientific and Ethical Considerations
This ELSI Friday Forum took place on January 12, 2024.
This ELSI Friday Forum took place on November 10, 2023.
The number of genomic loci identified to be associated with psychiatric disorders have substantially increased over the last decade. Alongside developments in polygenic embryo screening (PES; or PGT-P), the use of polygenic risk scores (PRS) to predict the genetic likelihood of polygenic traits (e.g., height, skin tone) and conditions (e.g., psychiatric disorders), it is now possible to screen embryos intended for invitro fertilization for genetic risk of psychiatric conditions such as schizophrenia or autism spectrum disorders.
The Center for Medical Ethics and Health Policy at Baylor College of Medicine is hiring a full-time Research Assistant I with interests in bioethics, social science, health policy, public health, epidemiology, or related field to work on an NIH-funded study examining the social, clinical, and ethical implications of using polygenic risk scores in child and adolescent psychiatry, as well as other studies exploring ethical, legal, and social implications (ELSI) of genomics. The research assistant will be part of an interdisciplinary team of researchers led by Stacey Pereira, PhD; Eric A.